SPIONs for cell labelling and tracking using MRI: magnetite or maghemite?† †Electronic supplementary information (ESI) available: pXRD, DLS, zeta potential, TEM, TGA, MRI and XANES. See DOI: 10.1039/c7bm00515f

نویسندگان

  • Michael Barrow
  • Arthur Taylor
  • Ana M. Fuentes-Caparrós
  • Jack Sharkey
  • Luke M. Daniels
  • Pranab Mandal
  • B. Kevin Park
  • Patricia Murray
  • Matthew J. Rosseinsky
  • Dave J. Adams
چکیده

Although there is extensive literature covering the biomedical applications of superparamagnetic iron oxide nanoparticles (SPIONs), the phase of the iron oxide core used is not often taken into account when cell labelling and tracking studies for regenerative medicine are considered. Here, we use a co-precipitation reaction to synthesise particles of both magnetite- (Fe3O4) and maghemite- (γ-Fe2O3) based cores and consider whether the extra synthesis step to make maghemite based particles is advantageous for cell tracking.

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منابع مشابه

SPIONs for cell labelling and tracking using MRI: magnetite or maghemite?†

Although there is extensive literature covering the biomedical applications of superparamagnetic iron oxide nanoparticles (SPIONs), the phase of the iron oxide core used is not often taken into account when cell labelling and tracking studies for regenerative medicine are considered. Here, we use a co-precipitation reaction to synthesise particles of both magnetite(Fe3O4) and maghemite(γ-Fe2O3)...

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Al(OH)3 facilitated synthesis of water-soluble, magnetic, radiolabelled and fluorescent hydroxyapatite nanoparticles† †Electronic supplementary information (ESI) available: Conjugation of NPs with dyes, radiolabelling for NPs, NMR spectra, XRD, IR, zeta potential, DLS size distribution, TEM images and TGA data of NPs, fluorescent images of NPs. See DOI: 10.1039/c5cc02259b Click here for additional data file.

[a] Division of Imaging Science, 4th Floor of Lambeth wing, St Thomas Hospital campus, King’s College London, SE1 7EH, London, UK [b] Department of physics, Strand campus, King’s College London, WC2R 2LS, London, UK [c] Department of Mathematical Science, Loughborough University, Loughborough, LE11 3TU, UK [d] School of Chemistry, University of Nottingham, Nottingham, NG7 2RD, UK [e] Department...

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2017